Health Effects

Direct effects
Several studies examined the impact of GMO on living organisms and often found direct negative effects.

  • “… we clearly proved very significant differences in weight growths for both males and females [rats], with a lower effect with the 11% diet in comparison to 33% and controls.”

  • “If all the data are taken together, […] it could be concluded that a GM-linked male renal toxicity is observed in this work. (Séralini, Cellier, Spiroux de Vendomois, 2007)

Indirect effects through pesticides
As outlined in many studies, the use of GMO increases the usage of pesticides (herbicide tolerant plants). Thus, to give a full picture of the results, the environmental and health aspects of the increase in pesticide usage have to be taken into account.

 Risk of Miscarriage
Pesticide exposure can have a devastating impact on abortion rates, as was found in several studies.

  •  “Preconception exposure to the pesticide active ingredients glyphosate, atrazine, carbaryl, and 2,4-D was associated with a 20–40% relative increase in risk;…”
  • “The herbicide glyphosate [Monsanto Roundup®] was associated with increased risks of late abortion, regardless of when exposure occurred.” (Arbuckle, Lin, Mery, 2001). 

Risk of Tumors & Cancer
Apart from increasing the abortion rates, pesticides also influence cell cycle regulation in general and thus affect the whole organism.

  • “Cell-cycle dysregulation is a hallmark of tumor cells and human cancers.” (p.245)

  • “Roundup 3plus, the glyphosate-based herbicide, induced cell cycle dysfunction as a result of synergy between glyphosate itself and the mixture of surfactants and permeabilizing agents present in the commercial product.” (p.246)

  • “Therefore, glyphosate-based pesticides are clearly of human health concern by inhalation in the vicinity of spraying. Our experiments detect very early a long term risk for humans since cancer may originate from a single cell several years or decades after the initial stress.” (Marc, Mulner-Lorillon, Bellé, 2004, (p 248))

 Human Cell Damage
Pesticides can remain in soils, plants, animals and human bodies long after exposure. This bio-accumulation can build in concentration over time, resulting in severe health problems.

  • “The first surprising results show that the four Roundup® herbicides and Glyphosate cause cellular death for all types of human cells, with comparable toxicity for each one but at different concentrations.”

  • “Indeed, the very weak Roundup concentration of 0.005% causes a very important cell death, lack of adhesion, shrinking, and fragmentation in apoptotic bodies.”

  • “All of the above effects are demonstrated below the recommended herbicide agricultural dilutions (from 104 ppm). This clearly confirms that the adjuvants in Roundup formulations are not inert. Moreover, the proprietary mixtures available on the market could cause cell damage and even death around residual levels to be expected, especially in food and feed derived from R formulation-treated crops.” (Benachour, Séralini, 2009)